产品货号：
GS4529
中文名称：
重组人TARC/CCL17
英文名称：
Recombinant Human Thymus and Activation Regulated Chemokine/CCL17
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 8.1kDa,a single non-glycosylated polypeptide chain containing 71 amino acids.
储存条件：冷冻（-20℃）
概述
Human CCL17 also known as thymus and activation-related chemokine(TARC)is encoded by the CCL17 gene located on the chromosome 16 in humans.It is expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently.CCL17 signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes.It plays an important role in skin diseases such as atopic dermatitis,bullous pemphigoid and mycosis fungoides.CCL17 has approximately 24 – 29%amino acid sequence identity with RANTES,MIP-1α,MIP-1β,MCP-1,MCP-2,MCP-3 and I-309.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人TARC/CCL17，TARC/CCL17, Human
储存条件：冷冻（-20℃）
概述
Human CCL17 also known as thymus and activation-related chemokine(TARC)is encoded by the CCL17 gene located on the chromosome 16 in humans.It is expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently.CCL17 signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes.It plays an important role in skin diseases such as atopic dermatitis,bullous pemphigoid and mycosis fungoides.CCL17 has approximately 24 – 29%amino acid sequence identity with RANTES,MIP-1α,MIP-1β,MCP-1,MCP-2,MCP-3 and I-309.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150mM NaCl. |
| 内毒素 | Less than 1 EU/μg of rHuTARC/CCL17 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S |
相关搜索：重组人TARC/CCL17，TARC/CCL17, Human